一、中心简介

首都医学科学创新中心（简称创新中心）是北京市新成立的具有独立法人资格的新型研发机构。创新中心以推动医学科学发展、改善人类健康为目标，开展生物医学研究，致力于提升医学科学创新与成果转化能力，提高疾病诊断和治疗水平。我们将汇聚世界高水平科学家及其科研团队，与首都医学教育和科学研究优质资源紧密合作，打造多学科交叉融合的科研平台，综合自由探索、医学目标导向、有组织科研等途径，实践新型科研模式和体制机制，逐步推进医教研产的深度融合，培养适应医学科学创新发展的优秀人才。

二、实验室介绍

黄亚平博士于2013年和2018年分别在武汉大学和清华大学获得学士和博士学位，之后在美国德克萨斯大学西南医学中心（UT Southwestern Medical Center）从事博士后研究，并于近日加入首都医学科学创新中心（CIMR）创建独立实验室。实验室将主要研究一类热休克蛋白（也叫分子伴侣）HSP40家族的重要生理学功能，尤其在维持基因组稳定性、天然免疫和糖代谢等途径中的功能和作用机制，及其在肿瘤、自体免疫疾病和代谢疾病中的作用。

三、实验室研究方向

本实验室将综合利用传统生物化学和细胞生物学、蛋白质组学、结构生物学、代谢组学、高通量筛选以及小鼠模型等手段，开展以下研究：

解析HSP40家族在DNA损伤修复、天然免疫及糖代谢等重要生理学过程中的作用和机制；

探究HSP40在肿瘤、自体免疫疾病和代谢疾病等人类复杂疾病发生发展和治疗中的作用；

开发基于HSP40的抗肿瘤、抗感染药物和方法。

代表性一作文章

Nature Communications, 2023, 14: 5246.

Cell Discovery, 2023, 9: 107.

Cell Discovery, 2019, 5: 57.

PNAS, 2018, 115: 9598-9603

(Another story about DNAJA2 regulating insulin signaling and glucose metabolism, coming soon)

四、招聘岗位

01【助理研究员】

1）主要职责

1. 在课题组长指导下独立开展研究工作；

2. 协助指导研究生工作以及撰写论文或基金申请。

2）任职要求

1. 具有肿瘤生物学、生物化学（尤其蛋白质结构生物化学）、细胞生物学、分子生物学、免疫学或其他相关生物医学领域的研究背景，已获得博士学位且至少有两年博士后研究经历；

2. 以第一作者身份在领域内主流期刊上发表过研究论文，能够独立开展研究工作；

3. 熟练掌握生物化学、细胞生物学、分子生物学、动物实验等基本实验操作；

4. 具备独立开展科研工作、指导研究生的能力，科学态度严谨；

5. 具备流利的英语读写和日常交流能力，能够使用英文撰写论文。

02【博士后】

1）主要职责

1. 在课题组长指导下独立开展研究工作；

2. 协助指导研究生工作以及撰写论文或基金申请。

2）任职要求

1. 具有肿瘤生物学、生物化学（尤其蛋白质结构生物化学）、细胞生物学、分子生物学、免疫学或其他相关生物医学领域的研究背景，即将获得博士学位或已获得博士学位（原则上不超过2年）；

2. 以第一作者身份在领域内主流期刊上发表过或即将发表研究论文，能够独立开展研究工作；

3. 熟练掌握生物化学、细胞生物学、分子生物学、动物实验等基本实验操作；

4. 具备独立开展科研工作、指导研究生的能力，科学态度严谨；

5. 具备流利的英语读写和日常交流能力，能够使用英文撰写论文。

五、福利待遇

1. 根据应聘者的工作经验和能力，提供具有市场竞争力的薪酬（详情面谈）；

2.享受五险一金、带薪年假、体检和补充医疗保险等；

3.支持个人职业发展，提供必要的工作相关专业培训。

六、申请方法

应聘者请将个人简历、研究兴趣或计划，以及2-3名推荐人的姓名及联系方式，以及其他能证明科研能力的相关电子文件发送到邮箱huangyp@cimrbj.ac.cn，邮件主题请注明“应聘者名字+具体应聘职位”。

联系人：黄老师

联系地址：北京市丰台区右安门外西头条10号-首都医学科学创新中心

本招聘长期有效，至招聘到合适人选为止。

ABOUT CIMR

The Chinese Institutes for Medical Research (CIMR) is a newly founded institution dedicated to fundamental and translational medical research. The CIMR is located at the main campus of the Capital Medical University, Beijing, China and committed to building a scientist-centered governance framework and fostering a diverse and inclusive work environment.For more information, please visit our website: www.cimrbj.ac.cn

Laboratory Introduction

The Huang laboratory at CIMR is interested in identifying the fundamental physiological functions of heat shock protein 40s (HSP40s) in critical biological pathways including genome maintenance, innate immunity and glucose metabolism, and their implications in pathogenesis of human diseases, such as cancer, autoimmune disease and metabolic disorder.  

A.Major Research Projects

a. Decoding the functions and functional mechanisms of HSP40 in critical biological pathways including genome maintenance, innate immunity and glucose metabolism.

b. Exploring the functions of HSP40 in the pathology and treatment of human disease, such as cancer, autoimmune disease and metabolic disorder.

c. Developing HSP40-based therapeutics for human diseases.

B.Representative Publications

Nature Communications, 2023, 14: 5246.

Cell Discovery, 2023, 9: 107.

Cell Discovery, 2019, 5: 57.

PNAS, 2018, 115: 9598-9603

(Another story about DNAJA2 regulating insulin signaling and glucose metabolism, coming soon)

Open Positions

Research assistant investigator

Main Responsibilities

a. Conducting research projects independently.

b. Assisting PI to mentor graduate students, write grant proposals and manuscripts.

Qualifications

a. Backgrounds in cancer biology, biochemistry (biochemistry and structural biology of proteins preferred), cell biology, molecular biology, immunology, or other related biomedical fields. A Ph.D degree and at least two years of postdoc experience is required.

b. Published research papers as the first author in reputable journals in the field.

c. Strong research experience in molecular biology, biochemistry, cell biology and/or mouse studies.

d. Self-motivated and independent researcher capable of independently conducting scientific research and assisting to supervise graduate students.

e. Proficient in English reading, writing, and daily communication. Capable of writing papers in English.

Postdoctoral Researcher

Main Responsibilities

a. Conducting research projects independently.

b. Assisting PI to mentor graduate students, write grant proposals and manuscripts.

Qualifications

a. Backgrounds in cancer biology, biochemistry (biochemistry and structural biology of proteins preferred), cell biology, molecular biology, immunology, or other related biomedical fields. Either about to obtain a Ph.D or recently obtained a Ph.D degree (ideally within the last 2 years).

b. Published or about to publish research papers as the first author in reputable journals in the field.

c. Strong research experience in molecular biology, biochemistry, cell biology and/or mouse studies.

d. Self-motivated and independent researcher capable of independently conducting scientific research and assisting to supervise graduate students.

e. Proficient in English reading, writing, and daily communication. Capable of writing papers in English.

Welfare Treatment

a.Competitive salary based on the job applicant's work experience and abilities (salary negotiable).

b. Social insurance, paid annual leave, physical examination and supplementary medical insurance, etc.

c.Supporting personal career development and providing necessary job related professional training.

How to apply

To apply, please send personal resume, research interest or plan, the names and contacts of 2-3 referees and other materials demonstrating research capabilities to huangyp@cimrbj.ac.cn, and indicate the applicant's name and specific job position in the email subject.

Contact person: Yaping Huang

This recruitment is valid for the long term until a suitable candidate is recruited.

信息来源于网络，如有变更请以原发布者为准。

来源链接：

https://mp.weixin.qq.com/s/rEd19xgVklTjSHIg8errOA