美国德州理工大学埃尔帕索健康科学中心2023年招聘博士后（CNS疾病相关致癌机制和免疫信号通路）

得克萨斯理工大学（Texas Tech University）创建于1923年，坐落在美国得克萨斯州的拉伯克市，是一所综合类公立研究型大学。校园占地1839英亩，是全美最大的校园之一。有学生4万多人，其中研究生有7000多人，法学院学生620人，得克萨斯理工大学设有150个大学本科、100多个硕士学位、68个博士学位教学计划。大学被美国卡内基高等教育机构分类列为国家级一级研究型大学（R1）。

HSC Post Doctoral Research Associate (Molecular Translational/Alberta)

Texas Tech University Health Sciences Center El Paso

Extended Job Title HSC Post Doctoral Research Associate (Molecular Translational/Alberta)

Org Level 1 Texas Tech Unv Hlth Sci Ctr El Paso

Position Description Performs specialized Post Doctoral work in the planning, conducting and/or supervision of original research at TTUHSC. Responsible for participating in a research project associated with Ph.D studies and the interpretation of the results of publication. Work is performed under supervision of graduate faculty members with evaluation based on accomplishment of assigned objectives and overall effectiveness of project. May supervise research and student assistants.

Requisition ID 34185BR

Travel Required Up to 25%

Major/Essential Functions

Involved in optimizing and test CRISPR-Cas9 gene-editing and delivery, plasmid DNA-gene therapy. Determine genetic modification, signaling regulation, molecular biology, histology and immune assays, and response for experimental and gene-editing based therapeutic evaluation, basic biomedicine tests as requested by advisor. Analyzing histological, pathological, cellular, genetic, molecular changes to evaluate the oncogenetic mechanisms and the immune signaling pathways associated to the CNS diseases.

Shall be Involved in analysis and utilization of both characterized and newly found peripheral and brain immune regulators, pro-and anti- inflammatory cytokines and immunocytes associated to brain tumor, and neuronal injury. Position involves molecular, genetic immunology, neuroimmunology, and cell biology assays. Testing the immunological and biological response of pro- and anti-inflammatory cytokines to neuropathogenesis.

Shall be responsible for in vitro and in vivo models to test systemic immunoresponses associated to cancer and neuronal injury, gene-based immunotherapy and brain targeting delivery.

Shall be response for CD34 stem cells, bone marrow stem cells, hPBMC, and primary neuronal cell isolation and cultures.

Shall be response for genetic, molecule and cellular analysis of nuclear protein, gene transcription, signaling pathways, cytokines, immunocytes, tumor cells and neuronal cells.

Shall be responsible for testing of gene-editing specificity and efficiency, therapeutic efficacy, and immune responses in vitro and in vivo.

Will need to perform isolation, identification and determination of nuclear, membrane, and cytoplasmic RNA, DNA, and protein.

Other duties as assigned to fulfill the research study.

Grant Funded? No

Minimum Hire Rate Compensation is commensurate upon the qualifications

Pay Basis Monthly

Work Location El Paso

Preferred Qualifications

Ph.D. in area of project specialization, knowledge of modern research practices, the methods, resources, and standards thereof or Ph.D. or equivalent doctorate (e.g., D.Sc., M.D.).

Ability to organize work effectively, conceptualize and prioritize objectives and exercise independent judgment based on an understanding of organizational policies and activities.

Ability to integrate resources, policies, and information for the determination of procedures, solutions, and other outcomes.

Ability to establish and maintain effective work relationships with other employees and the public.

Experience with gene delivery and nanoparticle-based imaging.

Campus HSC - El Paso

Department Ctr of Exc Disease/Bio Rsch EP

Required Attachments Cover Letter, Resume / CV, Transcript

Job Type Full Time

Pay Statement Compensation is commensurate upon the qualifications of the individual selected and budgetary guidelines of the hiring department, as well as, the institutional pay plan. For additional information, please reference the institutional pay plan on the Human Resources webpage.

Job Group Research Staff

Shift Day

EEO Statement As an EEO/AA employer, the Texas Tech University System and its components will not discriminate in our employment practices based on an applicant's race, ethnicity, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic information or status as a protected veteran.

Required Qualifications

PhD in area of project specialization Knowledge of modern research practices, the methods, resources, and standards thereof.

Ability to organize work effectively, conceptualize and prioritize objectives and exercise independent judgment based on an understanding of organizational policies and activities.

Ability to integrate resources, policies, and information for the determination of procedures, solutions and other outcomes.

Ability to establish and maintain effective work relationships with other employees and the public.

Ability to plan and allocate the workload of employees, providing direct training and supervision as needed.

Does this position work in a research laboratory? Yes

Are select agents used in this laboratory? Yes