丹麦哥本哈根大学药物设计与药理学系2023年招聘博士后职位

哥本哈根大学 （英文: University of Copenhagen; 丹麦文: Københavns Universitet；简称：UCPH / KU）坐落于丹麦王国首都哥本哈根，是丹麦最高学府，4EU＋联盟、国际研究型大学联盟、欧洲研究型大学联盟、欧洲首都大学联盟、欧洲大学协会成员。大学建于1479年，已有500多年历史，从最初只对社会名流开放，现已发展成一所学科全面、集教育与科研于一身的世界研究型大学。

作为欧洲的教育和科研机构之一，哥本哈根大学下属6个学院，包括36个部门以及200多个研究中心，综合排名跻身世界一流。哥本哈根大学位居2021软科世界大学学术排名第30位，2022泰晤士高等教育世界大学排名第96位，2022QS世界大学排名第79位，2022U.S. News世界大学排名第37位。

哥本哈根大学科研经费为全欧第4，仅次于剑桥大学、牛津大学和苏黎世联邦理工学院。截至2018年底，共有39位校友曾获得诺贝尔奖。

Postdoc in biopharmaceutic discovery at the department of Drug Design and Pharmacology

Copenhagen University

Denmark

October 19, 2023

Contact:N/A

Offerd Salary:Negotiation

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Contract Type:fixed-term position

Working Time:Negotigation

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Faculty of Health and Medical Sciences University of Copenhagen

We are looking for a highly motivated and dynamic postdoc for a 23 month position starting Jan 1st 2024 to work on the design and characterization of de novo microproteins for therapeutic applications. This is a DFF (Danmarks Frie Forskningsfond) funded position.

Information on the department can be found at: https: // ilf.ku.dk/

Our research The Rogers lab is working to find valuable new molecules: new in form, function, or both. We are particularly interested in exploring biopharmaceuticals, modified peptides and proteins, as next-generation therapeutics. This requires international collaboration, and working at the intersection of molecular biology, protein science, organic chemistry, biophysics and chemical biology.

Your job The emergence of deep learning-based methods is revolutionizing protein design. Small stable microproteins can now be generated routinely and reliably, and these can be imbued with functions such as binding to particular protein targets. Your tasks will be to apply the newest design methods to discover new binders, filter hits, order DNA constructs for expression, screen initial hits, express and purify the best designs and fully characterize binding biophysics to reveal their therapeutic potential.

Profile We are looking for a highly motivated and enthusiastic scientist with the following competencies and experience:

Essential experience and skills:

· You have a PhD in chemistry, biochemistry, biology, chemical biology or pharmacology

· You are highly experienced in molecular biology, protein expression and purification, biophysics of molecular interactions (e.g. SPR, BLI, ITC, circular dischorism, DSF).

· You have an active interest in new drug modalities

· Proficient communication skills and ability to work in teams

· Excellent English skills written and spoken

Desirable experience and skills:

· Knowledge of deep learning methods applied to protein design.

Place of employment

The place of employment is at the Department of Drug Design and Pharmacology, University of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment. Our research facilities include modern laboratories, facilities for protein expression and purification, computational resources, protein NMR, state-of-the-art biophysical equipment and analysis.

Terms of employment The average weekly working hours are 37 hours per week.

The position is a fixed-term position limited to a period of 23 months. The starting date is Jan 1st 2024.

Salary, pension and other conditions of employment are set in accordance with the Agreement between the Ministry of Taxation and AC (Danish Confederation of Professional Associations) or other relevant organisation. Currently, the monthly salary starts at 36,400 DKK/approx. 4,880 EUR (October 2023 level). Depending on qualifications, a supplement may be negotiated. The employer will pay an additional 17.1 % to your pension fund.

Foreign and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years.

The position is covered by the Job Structure for Academic Staff at Universities 2020.

Questions For further information please contact joseph.rogers@sund.ku.dk +45 23 84 00 87 ; www. sund.ku.dk

Foreign applicants may find this link useful: www. ism.ku.dk (International Staff Mobility).

Application procedure Your online application must be submitted in English by clicking ‘Apply now' below. Furthermore, your application must include the following documents/attachments – all in PDF format:

· Motivated letter of application (max. one page).

· CV incl. education, work/research experience, language skills and other skills relevant for the position.

· A certified/signed copy of a) PhD certificate and b) Master of Science certificate. If the PhD is not completed, a written statement from the supervisor will do.

· List of publications.

Deadline for applications:19 October, 23.59pm CET

We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

The further process After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

You can read about the recruitment process at https: // employment.ku.dk/faculty/recruitment-process/

The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.

Interviews are expected to be held in November 2023

The University of Copenhagen wish to reflect the diversity of society and encourage all qualified candidates to apply regardless of personal background.