意大利那不勒斯费德里科二世大学2023年招聘博士后职位（力学生物学）

那不勒斯费德里科二世大学， 即Università degli studi di Napoli Federico II 是那不勒斯市主要，是古老的大学学府。该大学于1224年由神圣罗马帝国皇帝和那不勒斯西西里国王腓特烈二世创建。最初是专门为了培养政府人员而建设的，其政治及司法学术传统较为突出。1978年9月7日大学正式以创始人的名字命名。学校是意大利第一所国属大学，这点就足够使他成为欧洲最古老的一所大学。该大学法学系和文学系德高望重，具有权威性，著名的希腊语言文化学者MARCELLO GIGANTE就在这里任教。该校已在90年代， 在意大利大学排名第二位，仅次于罗马大学。

那不勒斯费德里科二世大学获得中国教育部认证。它是欧洲第一所专门用来培养管理人员的学校，也是世界上最古老的大学之一。著名哲学家托马斯·阿奎纳就毕业于该校。

Postdoc In Mechanobiology

Universities and Institutes of Italy

Italy

January 01, 2024

Contact:N/A

Offerd Salary:Negotiation

Location:N/A

Working address:N/A

Contract Type:Other

Working Time:Full time

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Ref info:N/A

29 Oct 2023

Job Information

Organisation/Company

Department of Molecular Medicine and Medical Biotechnology, Federico II University of Naples, Italy

Research Field

Engineering

Researcher Profile

Recognised Researcher (R2)

Country

Italy

Application Deadline

1 Jan 2024 - 23:00 (UTC)

Type of Contract

To be defined

Job Status

Full-time

Hours Per Week

To be defined

Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme

Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

ABOUT THE POSITION We are looking for a postdoctoral researcher to join the Maiuri team at the Department of Molecular Medicine and Medical Biotechnology, Federico II University of Naples, Italy. Our group studies how cells sense and react to mechano-chemical stimuli coming from the surrounding micro-environment. Particularly, we are interested to investigate how those stimuli impact on the cell nucleus.

ONGOING RESEARCH PROJECTS

Nuclear Volume Cell and nuclear volumes are related and they constantly grow during the cell cycle. Since alterations of nuclear shape and size are well recognized hallmarks of cancer, we are interested in develop a method to measure the nuclear volume. Such method would allow us to study the nucleus-to-cell volume ratio in homeostasis, investigating not only its variation during the cell cycle but also how it is perturbed upon tumor transformation. Different techniques have been proposed to quantify the cell volume, with a variety of accuracy and sensitivity. However, none of them is able to measure simultaneously cell and nuclear volumes of individual cells in real-time https: // www. biorxiv.org/content/10.1101/2022.06.07.494975v1.

The intrinsic shape of the nucleus While the nuclei of most cells tend to be either round or oval, various diseases are associated with alterations in the shape of the cell nucleus. An abnormal nuclear shape and size is associated with cancer, in fact, it is one of the key diagnostic tools used in identifying malignant cells. Moreover, mutations in genes encoding lamins, one of the major structural components of the nucleoskeleton, are leading to a variety of disorders, including muscular dystrophy, dilated cardiomyopathy and progeria, and show cells with characteristic perturbation of the nuclear shape. Yet, the basic mechanisms linking cell and nuclear shape, and which is the intrinsic shape of the nucleus, are still unclear. https: // www. nature.com/articles/s41467-023-37064-0; https: // www. nature.com/articles/s41467-020-15910-9

TYPE OF CONTRACT Two years postdoctoral research fellowship (~30000欧元/y).

REQUIRED SKILLS PhD or equivalent degree in either Biotechnology, Bioengineering or other related fields. Proficiency in basic cell biology and imaging. Experience in molecular biology and/or in microfabrication, would be considered a plus.

RequirementsAdditional InformationWork Location(s)

Number of offers available

1

Company/Institute

Department of Molecular Medicine and Medical Biotechnology, Federico II University of Naples, Italy

Country

Italy

Where to apply

Website

https: // jobrxiv.org/job/department-of-molecular-medicine-and-medical- biotechnol…

Contact

Website

https:// www. unina.it/home

STATUS: EXPIRED