加拿大渥太华大学2024年招聘博士后职位（癌症表观遗传学和药物发现）

渥太华大学（University of Ottawa, 法语: Université d'Ottawa），简称渥大、uOttawa或UofO，始建于1848年，位于加拿大首都渥太华。渥太华大学是加拿大顶级研究型大学，加拿大最古老、全球规模最大的英法双语大学，G7国家U7顶级大学联盟成员，加拿大U15研究型大学联盟成员，英联邦大学协会成员；其前身是无玷圣母献主会在1848年创办的Bytown学院，1866年获得由维多利亚女王颁发的皇家特许状（Royal Charter ，加拿大仅有9所大学拥有），1965年重组出渥太华大学和圣保罗大学。

Postdoctoral Fellow in Cancer Epigenetics and Drug Discovery

University of Ottawa

Job Description

The Benoit lab at the University of Ottawa has a Postdoctoral Fellow position available to study human colorectal cancer and develop future therapeutic strategies to target cancer stem cells. The overarching goal of the Benoit lab is to develop new anticancer agents targeting essential elements of human colon cancer stem cell chromatin organization. The research led by the candidate will utilize patient-derived tissues, high-content imaging, organoid-based 3D bioprinting systems, high-throughput drug screening, genome-editing tools, and in vivo tumorigenesis models to evaluate the impact of small molecules on epigenetic regulation mechanisms essential to neoplastic stemness. The candidate will also work with bulk, spatial, and single-cell genomic analyses, spectral flow cytometry, and single-cell proteomics.

This position offers a unique opportunity for professional growth and development in a collaborative and dynamic research environment. We offer competitive salary and benefits package, with the possibility to renew/extend based on performance.‍

Published research work by the Benoit lab is found here:

https://pubmed.ncbi.nlm.nih.gov/?term=Benoit%20YD%20Ottawa&sort=date

Qualifications:

The position is for a PhD or MD/PhD holder, who graduated from a highly recognized academic program.

A strong background in cancer and/or stem cell biology is required. Advanced skills in cellular imaging, molecular biology, flow cytometry, mammalian cell culture, in vivo models, and genomic data analysis are highly desirable. Priority will be given to candidates with demonstrated computational biology knowledge and proficiency (Proficiency in data analysis using R or Python).

Ability to work independently, show self-initiative and attention to detail, and motivation to explore new techniques and concepts are essential.

Publication of relevant research work in recognized scientific journals is an asset.

Outstanding written and oral communication skills, team spirit, and adherence to highest ethical principles when collecting experimental data and working with laboratory animals are necessary.

Candidates can expect a positive, competitive, and success-oriented work environment, tailored to their personal career and publications goals. The successful candidate will engage in vibrant scientific discourse with the University of Ottawa molecular sciences and stem cell biologist community. Regular meetings with the PI will assure mutual expectations are met.

Only shortlisted candidates will be contacted.