美国加州大学旧金山分校2024年招聘博士后职位（脑肿瘤研究）

加利福尼亚大学旧金山分校（University of California, San Francisco），简称UCSF，位于美国加利福尼亚州旧金山， 是美国加利福尼亚大学系统的第二所公立大学，是世界著名的生命科学及医学研究教学中心。

UCSF Postdoctoral Scholar in Brain Tumor Research

Employer

University of California San Francisco, Brain Tumor Center, Raleigh Lab

Location

San Francisco, California

Salary

Salary is set according to UCSF standards for scientific experience and training level

Closing date

27 Sep 2024

The Raleigh Lab at the University of California San Francisco (UCSF) has 1 available position for a postdoctoral scholar with experience in wet lab techniques, and experience and/or interest in organoid models of brain cancer. Research in the Raleigh lab is focused on understanding the genomic, biochemical, and cellular drivers of tumor heterogeneity and evolution. Our team of basic scientists, bioinformaticians, and clinicians integrate human samples with diverse evolutionary and preclinical models to study cancer predisposition, tumorigenesis, and treatment resistance. In addition to showing how tumors develop and respond to therapy, our studies have elucidated mechanisms through neurofibromatosis tumor suppressor genes, epigenetic regulators, and the Hedgehog pathway that drive developmental patterning and stem cell homeostasis.

The Raleigh Lab is located at the UCSF Mission Bay Medical Center in the Brain Tumor Center on the 4th floor of the Helen Diller Family Comprehensive Cancer Center Research Building. Dr. Raleigh is a Physician Scientist in the Departments of Radiation Oncology, Neurological Surgery, and Pathology at UCSF. He is the Robert and Ruth Halperin Endowed Chair in Meningioma Research, and the Director of the Preclinical Therapeutics Core in the UCSF Brain Tumor Center. Eighty percent of his time is dedicated to research, and tne postdoctoral position that is available is focused on improving understanding of meningioma biology and treatments for patients with meningioma. All prior trainees in the Raleigh Lab have matriculated to successful independent careers in science and/or medicine.

Highly motivated individuals with doctoral training from broad scientific backgrounds are encouraged to apply. Ideal candidates will possess training in wet lab techniques, and have a drive to improve their experimental, analytic, scientific writing, and leadership skills. Mentorship and collaborative multidisciplinary science are essential in the Raleigh Lab, and candidates should have an aptitude for mentorship of junior lab members. Potential projects include investigations of inter-tumor heterogeneity (PMID: 35534562, 36227281, 29590631), intra-tumor heterogeneity (PMID: 32968068, 32023450, 35759011), predictive biomarkers (PMID: 37944590, 37963810, 38057502), signaling mechanisms (PMID: 30340023, 29202464, 38216572, https://www.researchsquare.com/article/rs-2577844/v1), and cancer stem cells (PMID: 31901251, 36067288, 38742767) using diverse experimental approaches, including functional genomic techniques (PMID: 33476305, 38216587) and spatial genomic techniques (PMID: 38760638).

To apply, please send CV and cover letter to david.raleigh@ucsf.edu. The Raleigh Lab website and additional information can be found at https://raleighlab.ucsf.edu/