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克利夫兰医学中心是世界最著名医疗机构之一，机构集合医疗、研究和教育三位一体，提供专业医疗和最新治疗方案的非营利性机构。克利夫兰医学中心始建于1921年2月28日 [1]，隶属于俄亥俄州一家非营利性公司——克利夫兰临床基金会，并由其经营。

Postdoctoral Fellow - Srinivasan Dasarathy Lab

Cleveland Clinic

Job Description

Highly motivated individuals with a PhD or MD/PhD in relevant area are encouraged to apply. This training position, under the direct supervision of a Cleveland Clinic Principal Investigator will provide practical training and experience in a research setting. This position is appointed through the Lerner Research Institute. The successful applicant will be able to demonstrate a commitment to research, a collaborative work ethic and strong communication skills, both written and verbal. This program is expected to be completed within 5 years.

Principal Investigator: Srinivasan Dasarathy, MD

Lerner Research Institute Department: Inflammation & Immunity

Lab Research Topics:

Cell signaling

RNA translation

Biochemistry

Gene editing

Imaging

For more information about the lab’s research, please visit: https://www.lerner.ccf.org/immuno/dasarathy/ or contact Dr. Dasarathy at dasaras@ccf.org.

Job Responsibilities:

Independent project design with the goal of data generation, analysis, interpretation and manuscript preparation

Culture of multiple cell lines, primary cell cultures

Basic molecular methods (real time PCR, immunoblots)

Confocal microscopy, fluorescent imaging

mRNA translational regulation

Education:

PhD or MD/PhD required

MD with relevant laboratory experience may substitute for PhD

Languages:

English Proficiency proof required for candidates arriving on J-1, J-2, or F1 + OPT visa status

Work Experience:

Previous experience in a research or academic setting. Graduate student experience meets this requirement.

Scientific writing experience

Additional Preferred Qualities:

Crispr/Cas9

Viral delivery systems

Handling mouse strains (not essential)

Protein expression, protein-protein interaction studies

Fraction separation, organelle isolation

Ability to analyze and perform mass spectrometry data for metabolites preferred but not essential

Physical Requirements:

Ability to perform work in a stationary position for extended periods

Ability to operate a computer and other office equipment

Ability to communicate and exchange accurate information

Ability to distinguish color

Manual dexterity to handle specimens and repair equipment

Ability to lift and transport equipment or specimens weighing up to 20 pounds

May be exposed to hazardous chemicals, bio-hazards, radioactive materials, etc.

Personal Protective Equipment:

PPE per institutional requirements; may vary by laboratory

Preferred Application Materials:

Cover letter

CV

Contact information for three references

All application materials should be submitted directly via email to Dr. Dasarathy at dasaras@ccf.org.

Keywords: Postdoc, Research, LRI, Crispr/Cas9, Skeletal muscle, Tissue specific deletion, Inducible vector systems, Reporter analyses, FRET/BRET, Post-translational modifications, Generate tagged constructs, Subcellular organelle studies

Pay Range

Minimum hourly: $0.01

Maximum hourly: $333,340.26

The pay range displayed on this job posting reflects the anticipated range for new hires. While the pay range is displayed as an hourly rate, Cleveland Clinic recruiters will clarify whether the compensation is hourly or salary. A successful candidate's actual compensation will be determined after taking factors into consideration such as the candidate's work history, experience, skill set, and education. This is not inclusive of the value of Cleveland Clinic's benefits package, which includes among other benefits, healthcare/dental/vision and retirement.